Preparation: Protein-A purified
Content: Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.
Solvent: 0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Storage: 4-8ºC without exposure to light. No precautions necessary during handling.

D-dimer is a fibrin degradation product, a small protein fragment present in the blood after a blood clot is degraded by fibrinolysis.

Purified human D-dimer adsorbed onto aluminum hydroxide gel

ABS 015-28 binds human D-dimer. Cross-reacts with directly coated D-monomer but not with directly coated fibrinogen.

ABS 015-28 also reacts with dog D-dimer

When tested in a pair with itself, with ABS 015-22 and a fibrinogen-specific polyclonal antibody, the epitope appears to relate to the neo-epitope formed by cleavage of D-dimer from fibrin.

ABS 015-028 binds free D-dimer in solution.

ABS 015-028 works as capture antibody in sandwich ELISA with biotinylated ABS 015-28 or ABS 015-22 as detection antibody.

Biotinylated ABS 015-028 works as detection antibody in sandwich ELISA with ABS 015-22 or ABS 015-28 as capture antibody.

The combination with ABS 015-28 as capture antibody and ABS 015-22B as detection antibody is recommended.

Due to reducing conditions in Western blotting ABS 015-22 binds the alpha-chain (12kDa) of D-Dimer, and not the entire D-Dimer complex.