Anti-D-dimer (human, dog)
Mouse monoclonal antibody, biotinylated
Cat.No. ABS 015-22B
Preparation: Biotinylated
Content: 100 μL, 1 mg/mL +/- 15%. See Certificate of Analysis for details.
Solvent: 0.01 M phosphate buffer, pH 7.4, with 0.14 M NaCl and 15 mM sodium azide
Storage: 4-8ºC without exposure to light. No precautions necessary during handling.
D-dimer is a fibrin degradation product, a small protein fragment present in the blood after a blood clot is degraded by fibrinolysis.
Purified human D-dimer adsorbed onto aluminum hydroxide gel
ABS 015-22 binds human D-dimer. Cross-reacts < 2% with directly coated D-monomer but not with directly coated fibrinogen.
ABS 015-22 also reacts with dog D-dimer
When tested in a pair with itself, with ABS 015-28 and with a fibrinogen-specific polyclonal antibody, the epitope appears to relate to the dimenzation site of D-dimer.
ABS 015-22 binds free D-dimer in solution.
ABS 015-022 works as capture antibody in sandwich ELISA with biotinylated ABS 015-22 or ABS 015-28 as detection antibody.
Biotinylated ABS 015-22 works as detection antibody in sandwich ELISA for D-dimer with itself (ABS 015-22) or ABS 015-28 as capture antibody.
The combination with ABS 015-28 as capture antibody and ABS 015-22B as detection antibody is recommended.
| Method | Usability | References |
| ELISA | Yes | |
| Immunoblotting | ||
| Immunohistochemistry |
